Chris Anderson put together his own
Predator style R/C airplane drone that can actually go on autonomous picture taking missions. After strapping a 7 mega-pixel Pentax camera to it, he installed a nice small GPS guidance system.
Once the landing gear is disengaged, the GPS system takes over and directs the planes through up to 20 predetermined waypoints. Chris points out all the details, but you'll need some R/C experience before attempting this project on your own.
NOTE: don't depend on R/C airplane insurance to cover it, autonomous airplanes were specifically excluded from last membership form I checked out. [Via