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The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary ...
Management Sciences for Health. Management Sciences for Health (MSH) is a global nonprofit organization based in Arlington, Virginia that provides governments, health organizations, and the private sector with strategies, tools, and management support to deliver high-functioning health systems. According to the organization’s website, since ...
Infobox references. α-Melanocyte-stimulating hormone ( α-MSH) is an endogenous peptide hormone and neuropeptide of the melanocortin family, with a tridecapeptide structure and the amino acid sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH 2. It is the most important of the melanocyte-stimulating hormones (MSHs) (also known ...
The Mississippi State Hospital ( MSH) is a psychiatric facility operated by the Mississippi Department of Mental Health. [1] It is located in the unincorporated community of Whitfield, Rankin County, Mississippi, [2] [3] along Mississippi Highway 468. [4] The 350-acre (140 ha) campus is 15 miles (24 km) southeast of Jackson, [5] between Jackson ...
Melanocortin. The melanocortins are a family of neuropeptide hormones which are the ligands of the melanocortin receptors. [1] The melanocortin system consists of melanocortin receptors, ligands, and accessory proteins. The genes of the melanocortin system are found in chordates. [2] Melanocortins were originally named so because their earliest ...
Infobox references. γ-Melanocyte-stimulating hormone ( γ-MSH) is an endogenous peptide hormone and neuropeptide. [1] It is a melanocortin, specifically, one of the three types of melanocyte-stimulating hormone (MSH), and is produced from proopiomelanocortin (POMC). [1] It is an agonist of the MC 1, MC 3, MC 4, and MC 5 receptors. [1]
Mount Sinai Hospital, founded in 1852, is one of the oldest and largest teaching hospitals in the United States. [2] It is located in East Harlem in the New York City borough of Manhattan, on the eastern border of Central Park stretching along Madison and Fifth Avenues, between East 98th Street and East 103rd Street. [3]
Pharmacology. Afamelanotide is a synthetic tridecapeptide and a structural analogue of α-melanocyte stimulating hormone (α-MSH). It is a melanocortin receptor agonist and binds predominantly to the melanocortin-1 receptor (MC1R). Its binding lasts longer than that of α-MSH.