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  2. Adrenocorticotropic hormone deficiency - Wikipedia

    en.wikipedia.org/wiki/Adrenocorticotropic...

    Adrenocorticotropic hormone deficiency is a rare disorder characterized by secondary adrenal insufficiency with minimal or no cortisol production and normal pituitary hormone secretion apart from ACTH. [3] ACTH deficiency may be congenital or acquired, and its symptoms are clinically similar to those of glucocorticoid deficiency.

  3. ACTH stimulation test - Wikipedia

    en.wikipedia.org/wiki/ACTH_stimulation_test

    The ACTH test (also called the cosyntropin, tetracosactide, or Synacthen test) is a medical test usually requested and interpreted by endocrinologists to assess the functioning of the adrenal glands' stress response by measuring the adrenal response to adrenocorticotropic hormone (ACTH; corticotropin) or another corticotropic agent such as tetracosactide (cosyntropin, tetracosactrin; Synacthen ...

  4. Adrenocorticotropic hormone - Wikipedia

    en.wikipedia.org/wiki/Adrenocorticotropic_hormone

    Adrenocorticotropic hormone ( ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. [1] It is also used as a medication and diagnostic agent. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological ...

  5. Adrenal insufficiency - Wikipedia

    en.wikipedia.org/wiki/Adrenal_insufficiency

    Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones. The adrenal glands—also referred to as the adrenal cortex—normally secrete glucocorticoids (primarily cortisol ), mineralocorticoids (primarily aldosterone ), and androgens.

  6. Glucocorticoid remediable aldosteronism - Wikipedia

    en.wikipedia.org/wiki/Glucocorticoid_remediable...

    However, in subjects with glucocorticoid-remediable aldosteronism, ACTH increases the activity of existing aldosterone synthase, resulting in an abnormally high rate of aldosterone synthesis and hyperaldosteronism. Diagnosis. Genetic testing is done to ascertain that the individual in question does indeed have the condition. Treatment

  7. Nelson's syndrome - Wikipedia

    en.wikipedia.org/wiki/Nelson's_syndrome

    Nelson's syndrome is a disorder that occurs in about one in four patients who have had both adrenal glands removed to treat Cushing's disease. In patients with pre-existing adrenocorticotropic hormone ()-secreting pituitary adenomas, loss of adrenal feedback following bilateral adrenalectomy can trigger the rapid growth of the tumor, leading to visual symptoms (e.g. bitemporal hemianopsia) and ...

  8. Pseudo-Cushing's syndrome - Wikipedia

    en.wikipedia.org/wiki/Pseudo-Cushing's_syndrome

    Pseudo-Cushing's syndrome. Pseudo-Cushing's syndrome or non-neoplastic hypercortisolism is a medical condition in which patients display the signs, symptoms, and abnormal cortisol levels seen in Cushing's syndrome. However, pseudo-Cushing's syndrome is not caused by a problem with the hypothalamic-pituitary-adrenal axis as Cushing's is; it is ...

  9. Congenital adrenal hyperplasia due to 21-hydroxylase ...

    en.wikipedia.org/wiki/Congenital_adrenal...

    Lower ACTH leads to reduced production of all the steroids, including androgens. According to 2018 Clinical Practice Guideline, glucocorticoid treatment is not recommended in asymptomatic individuals, however, if the symptoms of androgen excess are sufficient, dexamethasone treatment may be prescribed.

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