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Google LLC The Google logo used since 2015 Google's headquarters, the Googleplex Formerly Google Inc. (1998–2017) Company type Subsidiary Traded as NASDAQ: GOOGL, GOOG Industry Internet Cloud computing Computer software Computer hardware Artificial intelligence Advertising Founded September 4, 1998 ; 25 years ago (1998-09-04) [a] in Menlo Park, California, United States Founders Larry Page ...
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PDBsum. structure summary. Signaling lymphocytic activation molecule (SLAM) is a family of genes. Homophilic binding between SLAMs is involved in cell-to-cell adhesion during antigen presentation. [1] [2] Signaling lymphocytic activation molecules are a CD2-related surface receptor expressed by activated phagocytes, T helper cells, and ...
Description T cell activation.svg. The T lymphocyte activation pathway is triggered when a T cell encounters its cognate antigen, coupled to a MHC molecule, on the surface of an infected cell or a phagocyte. T cells contribute to immune defenses in two major ways: some direct and regulate immune responses; others directly attack infected or ...
Antigen presentation stimulates T cells to become either "cytotoxic" CD8+ cells or "helper" CD4+ cells.. A cytotoxic T cell (also known as T C, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8 + T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected by intracellular pathogens (such as viruses or bacteria), or ...
Linker for activation of T cells. The Linker for activation of T cells, also known as linker of activated T cells or LAT, is a protein involved in the T-cell antigen receptor signal transduction pathway which in humans is encoded by the LAT gene. [5] Alternative splicing results in multiple transcript variants encoding different isoforms.
Kinetic-segregation is a model proposed for the mechanism of T-cell receptor (TCR) triggering. [1] [2] It offers an explanation for how TCR binding to its ligand triggers T-cell activation, based on size-sensitivity for the molecules involved. Simon J. Davis and Anton van der Merwe, University of Oxford, proposed this model in 1996.
LeBron Raymone James Sr. ( / ləˈbrɒn / lə-BRON; born December 30, 1984) is an American professional basketball player for the Los Angeles Lakers of the National Basketball Association (NBA). Nicknamed " King James ", he is widely recognized as one of the greatest players in the history of the sport and is often compared to Michael Jordan in ...
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