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GW501516 (also known as GW-501,516, GW1516, GSK-516, Cardarine, and on the black market as Endurobol [1]) is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s.
Seladelpar, sold under the brand name Livdelzi, is a medication used for the treatment of primary biliary cholangitis. [1] It is used as the lysine dihydrate salt. [1] It is a PPARδ receptor agonist.
Elafibranor (INN [4]), sold under the brand name Iqirvo, is a medication used for the treatment of primary biliary cholangitis. [1] [5]Elafibranor is a dual PPARα/δ agonist.
Multiple derivatives of GW0742 core structure have been developed. One of the compounds has the thiazole ring replaced with an oxazole ring inhibited VDR-meditated transcription with IC 50 of 660 nM. [7]
A pulsed plasma thruster (PPT), also known as a Pulsed Plasma Rocket (PPR), or as a plasma jet engine (PJE), is a form of electric spacecraft propulsion. [1] PPTs are generally considered the simplest form of electric spacecraft propulsion and were the first form of electric propulsion to be flown in space, having flown on two Soviet probes (Zond 2 and Zond 3) starting in 1964. [2]
The Polish Workers' Party (Polish: Polska Partia Robotnicza, PPR) was a communist party in Poland from 1942 to 1948. It was founded as a reconstitution of the Communist Party of Poland (KPP) and merged with the Polish Socialist Party (PPS) in 1948 to form the Polish United Workers' Party (PZPR). [ 1 ]
Tetradecylthioacetic acid (TTA) is a synthetic fatty acid used as a nutritional supplement.. TTA acts as a peroxisome proliferator-activated receptor alpha (PPARα) agonist and increases mitochondrial fatty acid oxidation in vitro. [1]