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Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic.It is 20 to 40 times more potent than heroin and 100 times more potent than morphine; [9] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries.
The province's name was chosen by Queen Victoria, when the Colony of British Columbia (1858–1866), i.e., "the Mainland", became a British colony in 1858. [27] It refers to the Columbia District, the British name for the territory drained by the Columbia River, in southeastern British Columbia, which was the namesake of the pre-Oregon Treaty Columbia Department of the Hudson's Bay Company.
[139] [140] [141] In an effort to take the edge off of the console's software pricing disadvantage, Nintendo worked to lower manufacturing costs for Nintendo 64 cartridges, and leading into the 1997 holiday shopping season announced a new pricing structure which amounted to a roughly 15% price cut on both first-party and third-party games.