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PPAR agonists are drugs that act on peroxisome proliferator-activated receptors, which are involved in metabolism and inflammation. Learn about the different classes of PPAR agonists, such as PPAR-alpha, PPAR-gamma and PPAR-delta, and their applications in treating metabolic syndrome, diabetes and addiction.
Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993. [6]
PPAR-alpha is a protein that regulates fatty acid oxidation, ketogenesis, and gluconeogenesis in the liver. It is activated by fatty acids and fibrate drugs, and is involved in peroxisome proliferation and atherosclerosis.
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A list of notable deaths that occurred in 2024, sorted by date and name. Includes politicians, athletes, artists, actors, and other figures from various countries and fields.
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