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Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993. [6]
PPAR-alpha is a protein that regulates fatty acid oxidation, ketogenesis, and gluconeogenesis in the liver. It is activated by fatty acids and fibrate drugs, and is involved in peroxisome proliferation and atherosclerosis.
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PPARγ is a nuclear receptor protein that regulates gene expression and metabolism in adipose tissue and other tissues. Learn about its structure, function, ligands, genetics, and diseases related to PPARγ.
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