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Deficiency (<50 nmol/L): Europe 40%, US 24%, Canada 37% [2] Vitamin D deficiency or hypovitaminosis D is a vitamin D level that is below normal. It most commonly occurs in people when they have inadequate exposure to sunlight, particularly sunlight with adequate ultraviolet B rays (UVB).
Michael F. Holick ( / ˈhɒlɪk / HOLL-ik; [1] born 1946) is an American adult endocrinologist, specializing in vitamin D, such as the identification of both calcidiol, the major circulating form of vitamin D, and calcitriol, the active form of vitamin D. His work has been the basis for diagnostic tests and therapies for vitamin D-related ...
D014807. Legal status. In Wikidata. Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and for many other biological effects. [1] [2] [3] In humans, the most important compounds in this group are vitamin D 3 ( cholecalciferol) and vitamin D 2 ( ergocalciferol ).
In this disorder, vitamin D is believed to be involved in the development of the brain during the gestational period. Gestational vitamin D deficiency in rats is associated with reduced levels of neurotrophic factors NGF and GDNF. NGF is the nerve growth factor, which is involved in neurotransmission.
Osteomalacia is a disease characterized by the softening of the bones caused by impaired bone metabolism primarily due to inadequate levels of available phosphate, calcium, and vitamin D, or because of resorption of calcium. The impairment of bone metabolism causes inadequate bone mineralization . Osteomalacia in children is known as rickets ...
Ergocalciferol, also known as vitamin D2 and nonspecifically calciferol, is a type of vitamin D found in food and used as a dietary supplement. [3] As a supplement it is used to prevent and treat vitamin D deficiency. [4] This includes vitamin D deficiency due to poor absorption by the intestines or liver disease. [5]
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