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Akt/PKB signaling pathway. The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K ( phosphatidylinositol 3-kinase) and Akt ( protein kinase B ). Initial stimulation by one of the growth factors causes ...
Crystal structure of Akt-2-inhibitor complexes. [2] Protein kinase B ( PKB ), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration .
according to International Monetary Fund estimates [n 1] [1] Countries by nominal GDP in 2019 [n 2] > $20 trillion. $10–20 trillion. $5–10 trillion. $1–5 trillion. $750 billion – $1 trillion. $500–750 billion. $250–500 billion.
AKT1. RAC (Rho family)-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) protein domains. [5] It is commonly referred to as PKB, or by both names as "Akt/PKB".
ac·ro·nym (ăk ′ rə-nĭm′) n. 1. A word formed by combining the initial letters of a multipart name, such as NATO from N orth A tlantic T reaty O rganization or by combining the initial letters or parts of a series of words, such as radar from ra dio d etecting a nd r anging.
Transcription factor II D ( TFIID) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. RNA polymerase II holoenzyme is a form of eukaryotic RNA polymerase II that is recruited to the promoters of protein -coding genes in living cells. It consists of RNA polymerase II, a subset of general ...
The PK ( Russian: Пулемёт Калашникова, transliterated as Pulemyot Kalashnikova, or "Kalashnikov's machine gun") [4] is a belt-fed general-purpose machine gun, chambered for the 7.62×54mmR rimmed cartridge. Designed in the Soviet Union and currently in production in Russia, [1] the original PK machine gun was introduced in ...
Four UN members (Cuba, Liechtenstein, Monaco and North Korea) do not belong to the IMF hence their economies are not ranked below. Kosovo, despite not being a member of the United Nations, is a member of IMF. Taiwan is not a IMF member but it is still listed in the official IMF indices. Several leading GDP-per-capita (nominal) jurisdictions may ...