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PPAR-gamma agonists. PPARγ (gamma) is the main target of the drug class of thiazolidinediones (TZDs), used in diabetes mellitus and other diseases that feature insulin resistance. It is also mildly activated by certain NSAIDs (such as ibuprofen) and indoles, as well as from a number of natural compounds.
View/Edit Mouse. Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.
View/Edit Mouse. Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. [5] Together with peroxisome proliferator-activated receptor delta and peroxisome ...
In the field of molecular biology, the peroxisome proliferator–activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. [1] PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein ...
T3 or T3R - Tier 3 or Tier 3 Reinvestigation, now replace all NACLC. T5 and T5R - Tier 5 or Tier 5 Reinvestigation, now replace SSBI and SBPR respectively. Yankee White – An investigation required for personnel working with the President and Vice President of the United States. Obtaining such clearance requires, in part, an SSBI.
Delta Sigma Theta is the largest single organization historically founded for and by Black Women in the United States. Founded on January 13, 1913, at Howard University by twenty-two visionary collegiate students, Delta Sigma Theta is the first African American Greek-lettered organization for women based on the principles of servings others and ...
List of Delta Air Lines destinations. Delta Air Lines is a major United States airline based in Atlanta, Georgia. As of December 31, 2021, Delta's mainline aircraft fly to 242 destinations, serving 52 countries across six continents. The airline operates nine domestic hubs. [1]
A Bloom filter is a space-efficient probabilistic data structure, conceived by Burton Howard Bloom in 1970, that is used to test whether an element is a member of a set. False positive matches are possible, but false negatives are not – in other words, a query returns either "possibly in set" or "definitely not in set".