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Topics include (but are not limited to) adaptive and innate immune defenses as well as pathogen countermeasures, emerging pathogens, evolution, genomics and gene regulation, model host organisms, pathogen-cell biology, pathogenesis, prions, proteomics and signal transduction, rational vaccine design, structural biology, and virulence factors.
The Pathogen-Host Interactions database ( PHI-base) [1] is a biological database that contains manually curated information on genes experimentally proven to affect the outcome of pathogen-host interactions.
The vast majority of modern systems biology modeling software support SBML, which is the de facto standard for exchanging models of biological cellular processes. Some tools also support CellML, a standard used for representing physiological processes. The advantage of using standard formats is that even though a particular software application may eventually become unsupported and even ...
Infectious disease dynamics. Mathematical models need to integrate the increasing volume of data being generated on host - pathogen interactions. Many theoretical studies of the population dynamics, structure and evolution of infectious diseases of plants and animals, including humans, are concerned with this problem.
List of COVID-19 simulation models. COVID-19 simulation models are mathematical infectious disease models for the spread of COVID-19. [1] The list should not be confused with COVID-19 apps used mainly for digital contact tracing . Note that some of the applications listed are website-only models or simulators, and some of those rely on (or use ...
Pathogenomics does not focus exclusively on understanding pathogen-host interactions, however. Insight of individual or cooperative pathogen behavior provides knowledge into the development or inheritance of pathogen virulence factors. [13]
Comparison of software for molecular mechanics modeling. This is a list of computer programs that are predominantly used for molecular mechanics calculations. Biomolecular simulations, protein folding. Commercial version with multiple graphical front ends is sold by BIOVIA (as CHARMm), formerly Accelrys. Chemical reaction kinetics.
Compartmental models in epidemiology. Compartmental models are a very general modelling technique. They are often applied to the mathematical modelling of infectious diseases. The population is assigned to compartments with labels – for example, S, I, or R, ( S usceptible, I nfectious, or R ecovered). People may progress between compartments.