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PPAR-gamma agonists. PPARγ (gamma) is the main target of the drug class of thiazolidinediones (TZDs), used in diabetes mellitus and other diseases that feature insulin resistance. It is also mildly activated by certain NSAIDs (such as ibuprofen) and indoles, as well as from a number of natural compounds.
In the field of molecular biology, the peroxisome proliferator–activated receptors ( PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. [1] PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism ( carbohydrate, lipid, protein ...
View/Edit Mouse. Peroxisome proliferator-activated receptor alpha ( PPAR-α ), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. [5] Together with peroxisome proliferator-activated receptor delta and peroxisome ...
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View/Edit Mouse. Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.
Brunswick Golden Isles Airport ( IATA: BQK, ICAO: KBQK, FAA LID: BQK ), previously known as Glynco Jetport, is a county-owned public-use airport located five nautical miles (9 km) north of the central business district of Brunswick, a city in Glynn County, Georgia, United States. [2] It is mostly used for general aviation, but is also served by ...
Stafford Regional Airport ( ICAO: KRMN, FAA LID: RMN) is a public airport located three miles (5 km) southwest of the central business district of Stafford, the county seat of Stafford County, Virginia, United States. [1] The airport is southwest of the intersection of Route 630 and U.S. Route 1 near Interstate 95, approximately 40 miles (64 km ...
SkyMiles is the frequent-flyer program of Delta Air Lines that offers points (or "miles") to passengers traveling on most fare types, as well as to consumers who utilize Delta co-branded credit cards, which accumulate towards free awards such as airline tickets, business and first-class upgrades, and luxury products. [1]