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PPAR-gamma agonists. PPARγ (gamma) is the main target of the drug class of thiazolidinediones (TZDs), used in diabetes mellitus and other diseases that feature insulin resistance. It is also mildly activated by certain NSAIDs (such as ibuprofen) and indoles, as well as from a number of natural compounds.
In the field of molecular biology, the peroxisome proliferator–activated receptors ( PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. [1] PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism ( carbohydrate, lipid, protein ...
View/Edit Mouse. Peroxisome proliferator-activated receptor alpha ( PPAR-α ), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. [5] Together with peroxisome proliferator-activated receptor delta and peroxisome ...
View/Edit Mouse. Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.
T3 or T3R - Tier 3 or Tier 3 Reinvestigation, now replace all NACLC. T5 and T5R - Tier 5 or Tier 5 Reinvestigation, now replace SSBI and SBPR respectively. Yankee White – An investigation required for personnel working with the President and Vice President of the United States. Obtaining such clearance requires, in part, an SSBI.
Brunswick Golden Isles Airport ( IATA: BQK, ICAO: KBQK, FAA LID: BQK ), previously known as Glynco Jetport, is a county-owned public-use airport located five nautical miles (9 km) north of the central business district of Brunswick, a city in Glynn County, Georgia, United States. [2] It is mostly used for general aviation, but is also served by ...
Pentatricopeptide repeat. The pentatricopeptide repeat (PPR) is a 35- amino acid sequence motif. Pentatricopeptide-repeat-containing proteins are a family of proteins commonly found in the plant kingdom. They are distinguished by the presence of tandem degenerate PPR motifs [1] and by the relative lack of introns in the genes coding for them.
Insertion loss is defined as a ratio of the signal level in a test configuration without the filter installed ( ) to the signal level with the filter installed ( ). This ratio is described in decibels by the following equation: For passive filters, will be smaller than . In this case, the insertion loss is positive and measures how much smaller ...
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