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Infectious disease dynamics. Mathematical models need to integrate the increasing volume of data being generated on host - pathogen interactions. Many theoretical studies of the population dynamics, structure and evolution of infectious diseases of plants and animals, including humans, are concerned with this problem.
Quantitative microbiological risk assessment [1] (QMRA) is the process of estimating the risk from exposure to microorganisms . The process involves measuring known microbial pathogens or indicators and running a Monte Carlo simulation to estimate the risk of transfer. [1] If a dose-response model is available for the microbe, it be used to ...
COVID-19 simulation models are mathematical infectious disease models for the spread of COVID-19. [1] The list should not be confused with COVID-19 apps used mainly for digital contact tracing . Note that some of the applications listed are website-only models or simulators, and some of those rely on (or use) real-time data from other sources.
The discovery of disease -causing pathogens is an important activity in the field of medical science. Many viruses, bacteria, protozoa, fungi, helminths ( parasitic worms ), and prions are identified as a confirmed or potential pathogen. In the United States, a Centers for Disease Control and Prevention program, begun in 1995, identified over a ...
Source attribution. In the field of epidemiology, source attribution refers to a category of methods with the objective of reconstructing the transmission of an infectious disease from a specific source, such as a population, individual, or location. For example, source attribution methods may be used to trace the origin of a new pathogen that ...
Gain-of-function research ( GoF research or GoFR) is medical research that genetically alters an organism in a way that may enhance the biological functions of gene products. This may include an altered pathogenesis, transmissibility, or host range, i.e., the types of hosts that a microorganism can infect. This research is intended to reveal ...
Disease X. Colored Scanning electron microscope (SEM) image of SARS-CoV-2, speculated in 2020 as being the first virus to create Disease X [1] [2] [3] Disease X is a placeholder name that was adopted by the World Health Organization (WHO) in February 2018 on their shortlist of blueprint priority diseases to represent a hypothetical, unknown ...
Serial passage is the process of growing bacteria or a virus in iterations. For instance, a virus may be grown in one environment, and then a portion of that virus population can be removed and put into a new environment. This process is repeated with as many stages as desired, and then the final product is studied, often in comparison with the ...