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PPAR-gamma agonists. PPARγ (gamma) is the main target of the drug class of thiazolidinediones (TZDs), used in diabetes mellitus and other diseases that feature insulin resistance. It is also mildly activated by certain NSAIDs (such as ibuprofen) and indoles, as well as from a number of natural compounds.
In the field of molecular biology, the peroxisome proliferator–activated receptors ( PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. [1] PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism ( carbohydrate, lipid, protein ...
View/Edit Mouse. Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.
View/Edit Mouse. Peroxisome proliferator-activated receptor alpha ( PPAR-α ), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. [5] Together with peroxisome proliferator-activated receptor delta and peroxisome ...
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Delta purchased the aircraft at a steep discount: $19.6m each, well below their $33.2m production cost, which led Boeing to accuse the company of dumping the aircraft. Delta would later increase its order to a total of 145 A220 aircraft. For its wide-body fleet, Delta acquired 25 Airbus A330neo and 42 of the newly introduced Airbus A350 ...
Delta Air Lines is a major United States airline based in Atlanta, Georgia. As of December 31, 2021, Delta's mainline aircraft fly to 242 destinations, serving 52 countries across six continents. As of December 31, 2021, Delta's mainline aircraft fly to 242 destinations, serving 52 countries across six continents.
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