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PPAR-gamma agonists. PPARγ (gamma) is the main target of the drug class of thiazolidinediones (TZDs), used in diabetes mellitus and other diseases that feature insulin resistance. It is also mildly activated by certain NSAIDs (such as ibuprofen) and indoles, as well as from a number of natural compounds.
View/Edit Mouse. Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.
In the field of molecular biology, the peroxisome proliferator–activated receptors ( PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. [1] PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism ( carbohydrate, lipid, protein ...
Delta is testing a "Parallel Reality" screen in the Detroit airport that can show personalized flight information to up to 100 people at the same time.
Pattern recognition receptors ( PRRs) [1] play a crucial role in the proper function of the innate immune system. PRRs are germline-encoded host sensors, which detect molecules typical for the pathogens. [2] They are proteins expressed mainly by cells of the innate immune system, such as dendritic cells, macrophages, monocytes, neutrophils, as ...
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View/Edit Mouse. Peroxisome proliferator-activated receptor alpha ( PPAR-α ), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. [5] Together with peroxisome proliferator-activated receptor delta and peroxisome ...
Adi, 17 years, is spending the summer in his home village in the Danube Delta. One night he is brutally gaybashed on the street, the next day his world is turned upside-down. His parents no longer look at him as they did, and the seeming tranquillity of the village starts to crack. Cast. Ciprian Chiujdea as Adi; Laura Vasiliu as The Mother