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Institute for Disease Modeling (IDM) is an institute within the Global Health Division of the Bill and Melinda Gates Foundation. Established in 2008 as part of the Global Good Fund, a non-profit subsidiary of Intellectual Ventures (IV) funded by Bill and Melinda Gates, IDM has transitioned in mid-2020 to the Gates Foundation.
Infectious disease dynamics. Mathematical models need to integrate the increasing volume of data being generated on host - pathogen interactions. Many theoretical studies of the population dynamics, structure and evolution of infectious diseases of plants and animals, including humans, are concerned with this problem.
Compartmental models in epidemiology. Compartmental models are a very general modelling technique. They are often applied to the mathematical modelling of infectious diseases. The population is assigned to compartments with labels – for example, S, I, or R, ( S usceptible, I nfectious, or R ecovered). People may progress between compartments.
With the assistance of high throughput sequencing methods and in silico technologies, it is possible to detect, compare and catalogue many of these dynamic genomic events. Genomic diversity is important when detecting and treating a pathogen since these events can change the function and structure of the pathogen.
BioWatch is a United States federal government program to detect the release of pathogens into the air as part of a terrorist attack on major American cities. Reportedly operating in Philadelphia, New York City, Washington, DC, San Diego, Boston, Chicago, San Francisco, Atlanta, St. Louis, Houston, Los Angeles and 21 other cities, [1] the BioWatch program was created in 2001 in response to the ...
Forecasting systems are based on assumptions about the pathogen's interactions with the host and environment, the disease triangle. [1] The objective is to accurately predict when the three factors – host, environment, and pathogen – all interact in such a fashion that disease can occur and cause economic losses.
Modelling biological systems. Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology [b] [1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems.
PhytoPath was a bioinformatics resource launched in 2012, [1] which integrated genome scale data from important plant pathogenic species with literature-curated information about the phenotypes of host infection available from the Pathogen-Host Interaction database (PHI-base). It provides access to complete genome assembly and gene models from priority crop and model phytopathogenic species of ...
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