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Effective dose (pharmacology) In pharmacology, an effective dose (ED) or effective concentration (EC) is the dose or concentration of a drug that produces a biological response. [1][2] The term "effective dose" is used when measurements are taken in vivo, while "effective concentration" is used when the measurements are taken in vitro. [3]
A dose–response curve is a coordinate graph relating the magnitude of a dose (stimulus) to the response of a biological system. A number of effects (or endpoints) can be studied. The applied dose is generally plotted on the X axis and the response is plotted on the Y axis. In some cases, it is the logarithm of the dose that is plotted on the ...
Therapeutic index. The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug. It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1] The related terms therapeutic window or safety window refer to a ...
In membrane science and technology, concentration polarization refers to the emergence of concentration gradients at a membrane/solution interface resulted from selective transfer of some species through the membrane under the effect of transmembrane driving forces. [4] Generally, the cause of concentration polarization is the ability of a ...
Trough level. In medicine and pharmacology, a trough level or trough concentration (Ctrough) is the concentration reached by a drug immediately before the next dose is administered, [1][2] often used in therapeutic drug monitoring. The name comes from the idea that on a graph of concentration versus time, the line forms a U-shaped trough at the ...
Educational specialist. The Education Specialist, also referred to as Educational Specialist or Specialist in Education (Ed.S., EdS or S.Ed.), is a specialist degree in education which is an advanced professional degree in the U.S. that is designed to provide knowledge and theory in the field of education beyond the master's degree level. [1]
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