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In the field of molecular biology, the peroxisome proliferator–activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. [1] PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism (carbohydrate, lipid, protein ...
PPARγ (gamma) is the main target of the drug class of thiazolidinediones (TZDs), used in diabetes mellitus and other diseases that feature insulin resistance. It is also mildly activated by certain NSAIDs (such as ibuprofen) and indoles, as well as from a number of natural compounds. Known inhibitors include the experimental agent GW-9662.
View/Edit Mouse. Peroxisome proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. [5] Together with peroxisome proliferator-activated receptor delta and peroxisome ...
T3 or T3R - Tier 3 or Tier 3 Reinvestigation, now replace all NACLC. T5 and T5R - Tier 5 or Tier 5 Reinvestigation, now replace SSBI and SBPR respectively. Yankee White – An investigation required for personnel working with the President and Vice President of the United States. Obtaining such clearance requires, in part, an SSBI.
View/Edit Mouse. Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.
View/Edit Mouse. Peroxisome proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear receptor subfamily 1, group C, member 3) is a type II nuclear receptor functioning as a transcription factor that in humans is encoded by the PPARG gene. [5][6][7]
A pulsed plasma thruster (PPT), also known as a Pulsed Plasma Rocket (PPR), or as a plasma jet engine (PJE), is a form of electric spacecraft propulsion. [1] PPTs are generally considered the simplest form of electric spacecraft propulsion and were the first form of electric propulsion to be flown in space, having flown on two Soviet probes (Zond 2 and Zond 3) starting in 1964. [2]
A Bloom filter is a space-efficient probabilistic data structure, conceived by Burton Howard Bloom in 1970, that is used to test whether an element is a member of a set. False positive matches are possible, but false negatives are not – in other words, a query returns either "possibly in set" or "definitely not in set".