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Depression is a mental state of low mood and aversion to activity. [3] It affects more than 280 million people of all ages (about 3.5% of the global population). [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5] Depressed people often experience loss of motivation or interest in, or reduced pleasure or ...
Major depressive disorder ( MDD ), also known as clinical depression, is a mental disorder [9] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [10] the term was adopted by the American ...
Biology of depression. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [1] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or situational causes.
Melancholic depression, or depression with melancholic features, is a DSM-IV and DSM-5 specifier of depressive disorders. The specifier is used to distinguish clinically relevant subsets of causes and symptoms [1] that have the potential to influence treatment.
Antidepressants, mood stabilizers, antipsychotics [1] A mood disorder, also known as an affective disorder, is any of a group of conditions of mental and behavioral disorder [2] where a disturbance in the person's mood is the main underlying feature. [3] The classification is in the Diagnostic and Statistical Manual of Mental Disorders (DSM ...
Depression (kinesiology), an anatomical term of motion, refers to downward movement, the opposite of elevation. Depression (physiology), a reduction in a biological variable or the function of an organ. Central nervous system depression, physiological depression of the central nervous system that can result in loss of consciousness.
In the mid-20th century, researchers theorized that depression was caused by a chemical imbalance in neurotransmitters in the brain, a theory based on observations made in the 1950s of the effects of reserpine and isoniazid in altering monoamine neurotransmitter levels and affecting depressive symptoms. [32]
Atypical depression is defined in the DSM -IV as depression that shares many of the typical symptoms of major depressive disorder or dysthymia but is characterized by improved mood in response to positive events. In contrast to those with atypical depression, people with melancholic depression generally do not experience an improved mood in ...
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