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PPAR-gamma agonists. PPARγ (gamma) is the main target of the drug class of thiazolidinediones (TZDs), used in diabetes mellitus and other diseases that feature insulin resistance. It is also mildly activated by certain NSAIDs (such as ibuprofen) and indoles, as well as from a number of natural compounds.
In the field of molecular biology, the peroxisome proliferator–activated receptors ( PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. [1] PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism ( carbohydrate, lipid, protein ...
View/Edit Mouse. Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.
View/Edit Mouse. Peroxisome proliferator-activated receptor alpha ( PPAR-α ), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. [5] Together with peroxisome proliferator-activated receptor delta and peroxisome ...
Delta Air Lines is a major United States airline based in Atlanta, Georgia. As of December 31, 2021, Delta's mainline aircraft fly to 242 destinations, serving 52 countries across six continents. As of December 31, 2021, Delta's mainline aircraft fly to 242 destinations, serving 52 countries across six continents.
Background. Riley Testut started developing GBA4iOS, the predecessor of Delta, during his senior year at Richardson High School along with his friend Paul Thorsen. It was a emulator of the Game Boy Advance for the iPhone. iOS users had to sideload the emulator via a loophole called the "Date Trick", where the app is allowed to be downloaded and installed via the Safari browser, without needing ...
Pattern recognition receptors ( PRRs) [1] play a crucial role in the proper function of the innate immune system. PRRs are germline-encoded host sensors, which detect molecules typical for the pathogens. [2] They are proteins expressed mainly by cells of the innate immune system, such as dendritic cells, macrophages, monocytes, neutrophils, as ...
Delta Air Lines Flight 1141 was a scheduled domestic passenger flight between Dallas/Fort Worth, Texas and Salt Lake City, Utah. On August 31, 1988, the flight, using a Boeing 727-200 series aircraft, crashed during takeoff, resulting in 14 deaths and 76 injuries of the 108 on board.