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Compartmental models are a very general modelling technique. They are often applied to the mathematical modelling of infectious diseases. The population is assigned to compartments with labels – for example, S, I, or R, ( S usceptible, I nfectious, or R ecovered). People may progress between compartments. The order of the labels usually shows ...
Infectious disease dynamics. Mathematical models need to integrate the increasing volume of data being generated on host - pathogen interactions. Many theoretical studies of the population dynamics, structure and evolution of infectious diseases of plants and animals, including humans, are concerned with this problem.
Pathogenesis is a qualitative description of the process by which an initial infection causes disease. [2] Viral disease is the sum of the effects of viral replication on the host and the host's subsequent immune response against the virus. [3] Viruses are able to initiate infection, disperse throughout the body, and replicate due to specific ...
Multi-agent systems. An agent-based model ( ABM) is a computational model for simulating the actions and interactions of autonomous agents (both individual or collective entities such as organizations or groups) in order to understand the behavior of a system and what governs its outcomes. It combines elements of game theory, complex systems ...
Pathogenomics is a field which uses high-throughput screening technology and bioinformatics to study encoded microbe resistance, as well as virulence factors (VFs), which enable a microorganism to infect a host and possibly cause disease.
Pathogen transmission. In medicine, public health, and biology, transmission is the passing of a pathogen causing communicable disease from an infected host individual or group to a particular individual or group, regardless of whether the other individual was previously infected. [1] The term strictly refers to the transmission of ...
Modelling biological systems is a significant task of systems biology and mathematical biology. [a] Computational systems biology [b] [1] aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems. It involves the use of computer simulations of ...
Quantitative microbiological risk assessment [1] (QMRA) is the process of estimating the risk from exposure to microorganisms . The process involves measuring known microbial pathogens or indicators and running a Monte Carlo simulation to estimate the risk of transfer. [1] If a dose-response model is available for the microbe, it be used to ...