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PPAR agonists are drugs that act on peroxisome proliferator-activated receptors, which are involved in metabolism and inflammation. Learn about the different classes of PPAR agonists, such as PPAR-alpha, PPAR-gamma and PPAR-delta, and their applications in treating metabolic syndrome, diabetes and addiction.
PPARγ is a nuclear receptor protein that regulates gene expression and metabolism in adipose tissue and other tissues. Learn about its structure, function, ligands, genetics, and diseases related to PPARγ.
PPAR-alpha is a protein that regulates fatty acid oxidation, ketogenesis, and gluconeogenesis in the liver. It is activated by fatty acids and fibrate drugs, and is involved in peroxisome proliferation and atherosclerosis.
Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993. [6]
PPARG is a gene that encodes PPAR-gamma, a transcription factor that regulates adipocyte differentiation, lipid uptake, and insulin sensitivity. PPARG is activated by various fatty acids, phytocannabinoids, and thiazolidinediones, and is involved in inflammation, cholesterol transport, and cancer.
Q Clearance is a security clearance issued by the Department of Energy that allows access to classified information up to and including TOP SECRET data with the special designation: Restricted Data (TS//RD). Learn more about the different security clearance levels, designations, and investigations in the U.S. government.
A county-owned public-use airport in Glynn County, Georgia, serving Brunswick and the Golden Isles. It has one runway, one commercial airline (Delta Connection), and hosts air shows and events.
A Bloom filter is a probabilistic data structure that tests whether an element is in a set, with low space and time complexity. It uses k hash functions to map elements to a bit array, and returns false positives but no false negatives.