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Prognosis. Death usually occurs during early adulthood. Frequency. around 1 in 500,000 [ 5 ] Epidermolysis bullosa (EB) is a group of rare medical conditions that result in easy blistering of the skin and mucous membranes. Blisters occur with minor trauma or friction and are painful. Its severity can range from mild to fatal. [ 7 ]
A subunit vaccine is a vaccine that contains purified parts of the pathogen that are antigenic, or necessary to elicit a protective immune response. [1] [2] Subunit vaccine can be made from dissembled viral particles in cell culture or recombinant DNA expression, [3] in which case it is a recombinant subunit vaccine.
The vaccine contains 50 mcg of purified polysaccharide for each of the serogroups (A, C, Y, and W135) in a lyophilized form. The active pharmaceutical ingredient of the C, Y, and W-135 serogroups is sialic acid. Phosphate is an API for serogroup A. Lactose is used as a stabilizer. As a precautionary measure, mercury is not used in the vaccine ...
Jonny Kennedy. Jonathan "Jonny" Kennedy (4 November 1966 – 26 September 2003) was a British man who had a rare inherited condition known as dystrophic epidermolysis bullosa (EB or DEB). Kennedy ultimately died of skin cancer, a complication of EB.
Epidermolysis bullosa simplex. Epidermolysis bullosa simplex (EBS) is a disorder resulting from mutations in the genes encoding keratin 5 or keratin 14. [1]: 598 [2] It is one of the major forms of epidermolysis bullosa, a group of genetic conditions that cause the skin to be very fragile and to blister easily. [3]
Embryoid bodies (EBs) are three-dimensional aggregates formed by pluripotent stem cells. These include embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC) EBs are differentiation of human embryonic stem cells into embryoid bodies comprising the three embryonic germ layers. They mimic the characteristics seen in early-stage embryos.
General Dynamics Electric Boat[2] (GDEB) is a subsidiary of General Dynamics Corporation. It has been the primary builder of submarines for the United States Navy for more than 100 years. The company's main facilities are a shipyard in Groton, Connecticut, a hull-fabrication and outfitting facility in Quonset Point, Rhode Island, and a design ...
Electron-beam physical vapor deposition, or EBPVD, is a form of physical vapor deposition in which a target anode is bombarded with an electron beam given off by a charged tungsten filament under high vacuum. The electron beam causes atoms from the target to transform into the gaseous phase. These atoms then precipitate into solid form, coating ...