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COVID-19 simulation models are mathematical infectious disease models for the spread of COVID-19. [1] The list should not be confused with COVID-19 apps used mainly for digital contact tracing. Note that some of the applications listed are website-only models or simulators, and some of those rely on (or use) real-time data from other sources.
Mathematical models can project how infectious diseases progress to show the likely outcome of an epidemic (including in plants) and help inform public health and plant health interventions. Models use basic assumptions or collected statistics along with mathematics to find parameters for various infectious diseases and use those parameters to ...
Its aim is to support public health measures and surveillance by facilitating understanding of the spread and evolution of pathogens. The Nextstrain platform was begun in 2015. [ 2 ] Code developed by Nextstrain is made publicly available, via, for example github.com and its data is available and viewable in accessible form via the pages at the ...
Pathogen-associated molecular patterns (PAMPs) are small molecular motifs conserved within a class of microbes, but not present in the host. [1] They are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals. [2] This allows the innate immune system to recognize pathogens and thus ...
Gain-of-function research (GoF research or GoFR) is medical research that genetically alters an organism in a way that may enhance the biological functions of gene products. This may include an altered pathogenesis, transmissibility, or host range, i.e., the types of hosts that a microorganism can infect. This research is intended to reveal ...
Quantitative microbiological risk assessment [ 1] (QMRA) is the process of estimating the risk from exposure to microorganisms . The process involves measuring known microbial pathogens or indicators and running a Monte Carlo simulation to estimate the risk of transfer. [ 1] If a dose-response model is available for the microbe, it be used to ...
Pathogenesis is a qualitative description of the process by which an initial infection causes disease. [2] Viral disease is the sum of the effects of viral replication on the host and the host's subsequent immune response against the virus. [3] Viruses are able to initiate infection, disperse throughout the body, and replicate due to specific ...
The discovery of disease -causing pathogens is an important activity in the field of medical science. Many viruses, bacteria, protozoa, fungi, helminths (parasitic worms), and prions are identified as a confirmed or potential pathogen. In the United States, a Centers for Disease Control and Prevention program, begun in 1995, identified over a ...
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