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PPAR-gamma agonists. PPARγ (gamma) is the main target of the drug class of thiazolidinediones (TZDs), used in diabetes mellitus and other diseases that feature insulin resistance. It is also mildly activated by certain NSAIDs (such as ibuprofen) and indoles, as well as from a number of natural compounds.
Background. Riley Testut started developing GBA4iOS, the predecessor of Delta, during his senior year at Richardson High School along with his friend Paul Thorsen. It was a emulator of the Game Boy Advance for the iPhone. iOS users had to sideload the emulator via a loophole called the "Date Trick", where the app is allowed to be downloaded and installed via the Safari browser, without needing ...
Delta Air Lines planes parked on a taxiway at Kansas City International Airport. As of May 2024, the Delta Air Lines fleet consists of 989 mainline aircraft, making it the largest commercial airline fleet in the world. Delta Air Lines operates a fleet manufactured by Airbus and Boeing. Delta operates the world's largest fleets of the Airbus A220, Boeing 717, and Boeing 757, the largest ...
View/Edit Mouse. Peroxisome proliferator-activated receptor alpha ( PPAR-α ), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning as a transcription factor that in humans is encoded by the PPARA gene. [5] Together with peroxisome proliferator-activated receptor delta and peroxisome ...
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View/Edit Mouse. Peroxisome proliferator-activated receptor delta (PPAR-delta), or (PPAR-beta), also known as Nuclear hormone receptor 1 (NUC1) is a nuclear receptor that in humans is encoded by the PPARD gene. [5] This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.
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In the field of molecular biology, the peroxisome proliferator–activated receptors ( PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. [1] PPARs play essential roles in the regulation of cellular differentiation, development, and metabolism ( carbohydrate, lipid, protein ...