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US influenza statistics by flu season. From the Centers for Disease Control and Prevention page called "Disease Burden of Flu": "Each year CDC estimates the burden of influenza in the U.S. CDC uses modeling to estimate the number of flu illnesses, medical visits, hospitalizations, and deaths related to flu that occurred in a given season.
Viral vector vaccines enable antigen expression within cells and induce a robust cytotoxic T cell response, unlike subunit vaccines which only confer humoral immunity. [7] [17] In order to transfer a nucleic acid coding for a specific protein to a cell, the vaccines employ a variant of a virus as its vector.
The rotavirus vaccine is a vaccine used to protect against rotavirus infections, which are the leading cause of severe diarrhea among young children. [6] The vaccines prevent 15–34% of severe diarrhea in the developing world and 37–96% of the risk of death among young children due to severe diarrhea. [6]
2003 – First vaccine for Argentine hemorrhagic fever. [16] 2006 – First vaccine for human papillomavirus (which is a cause of cervical cancer) 2006 – First herpes zoster vaccine for shingles; 2011 – First vaccine for non-small-cell lung carcinoma (comprises 85% of lung cancer cases) 2012 – First vaccine for hepatitis E [17]
Inactivated vaccines have a reduced ability to produce a robust immune response for long-lasting immunity when compared to live attenuated vaccines. [3] Adjuvants and boosters are often required to produce and maintain protective immunity. [10] [16] Pathogens must be cultured and inactivated for the creation of killed whole-organism vaccines.
By mid-February 2021, significant increases in manufacturing and delivery of vaccines in conjunction with a recommendation by NACI to extend second dose administration to a maximum of 16 weeks resulted in a larger ramp-up in vaccine delivery across the nation and by July 2021, Canada's vaccine supply had grown to allow a return to shortened ...
Ebola vaccines are vaccines either approved or in development to prevent Ebola. As of 2022, there are only vaccines against the Zaire ebolavirus. The first vaccine to be approved in the United States was rVSV-ZEBOV in December 2019. [9] [10] It had been used extensively in the Kivu Ebola epidemic under a compassionate use protocol. [11]
The 100th anniversary of the BCG vaccine was in 2021. [11] It remains the only vaccine licensed against tuberculosis, which is an ongoing pandemic . Tuberculosis elimination is a goal of the World Health Organization (WHO), although the development of new vaccines with greater efficacy against adult pulmonary tuberculosis may be needed to make ...
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