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v. t. e. In the United States, prescription monitoring programs ( PMPs) or prescription drug monitoring programs ( PDMPs) are state-run programs which collect and distribute data about the prescription and dispensation of federally controlled substances and, depending on state requirements, other potentially abusable prescription drugs.
Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood. Its main focus is on drugs with a narrow therapeutic range, i.e. drugs that can easily be under- or overdosed. [1] TDM aimed at improving patient care by individually adjusting the dose ...
Interleukin 2. Interleukin-2 ( IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16 kDa protein [5] that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity.
Ixekizumab is a complete monoclonal antibody of the subclass IgG 4, consisting of two light chains and two heavy chains linked by disulfide bridges. Both heavy chains are glycosylated at the asparagine in position 296. In the hinge region, a serine is replaced by a proline to reduce formation of half-antibodies and heterodimers in the ...
Trough level. In medicine and pharmacology, a trough level or trough concentration ( Ctrough) is the concentration reached by a drug immediately before the next dose is administered, [1] [2] often used in therapeutic drug monitoring. The name comes from the idea that on a graph of concentration versus time, the line forms a U-shaped trough at ...
Number of yearly U.S. opioid overdose deaths from all opioid drugs. U.S. yearly overdose deaths, and the drugs involved. Among the 108,000 deaths in 2022, the largest share was related to fentanyl and other synthetic opioids (73,838 deaths). Total drug overdose deaths in the United States. There is an ongoing opioid epidemic (also known as the opioid crisis) in the United States, originating ...
Uppsala Monitoring Centre ( UMC ), located in Uppsala, Sweden, is the field name for the World Health Organization Collaborating Centre for International Drug Monitoring. UMC works by collecting, assessing and communicating information from member countries' national pharmacovigilance centres in regard to the benefits, harm, effectiveness and ...
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